HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: CHD9 (Q3L8U1)
Chromodomain-helicase-DNA-binding protein 9 (CHD-9) (EC 3.6.4.12) (ATP-dependent helicase CHD9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin-remodeling factor CHROM1) (Kismet homolog 2) (PPAR-alpha-interacting complex protein 320 kDa) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein)
Gene: CHD9

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23667531
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 2897
+	Hs
		818550 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		CHD7_HUMAN (1-2890): 0: 2275: 47.36
+	Mm
		57186 Q60I23_MOUSE (1-317): 7.89e-75: 234: 96.24		CHD7_MOUSE (1-2890): 0: 2266: 47.16
+	Hs
		727814 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		CHD7_HUMAN (1-2890): 0: 2275: 47.36
+	Hs
		818841 SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57		CHD7_HUMAN (1-2890): 0: 2275: 47.36
+	Hs
		818484 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		CHD8_HUMAN (1-2696): 0: 1790: 46.84
+	Hs
		229339 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		SMCA5_HUMAN (708-1762): 0: 866: 25.19
+	Mm
		1142014 Q60I23_MOUSE (1-317): 7.89e-75: 234: 96.24		SMCA5_MOUSE (754-1762): 0: 866: 26.21
+	Hs
		818056 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		CHD4_HUMAN (515-1605): 0: 820: 27.71
+	Hs
		817986 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		CHD3_HUMAN (440-1914): 0: 818: 23.97
+	Mm
		1142004 Q60I23_MOUSE (1-317): 7.89e-75: 234: 96.24		CHD4_MOUSE (515-1605): 0: 816: 27.71
+	Mm
		818727 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		CHD4_MOUSE (515-1605): 0: 816: 27.71
+	Hs
		658738 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		SMCA1_HUMAN (751-1756): 0: 860: 26.03
+	Hs
		727736 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		CHD3_HUMAN (440-1914): 0: 818: 23.97
+	Hs
		1059891 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		CHD4_HUMAN (515-1605): 0: 820: 27.71
+	Hs
		818279 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		CHD6_HUMAN (2059-2892): 2.41e-161: 563: 22.69
+	Hs
		727779 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		CHD6_HUMAN (2059-2892): 2.41e-161: 563: 22.69
+	Hs
		817810 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		SMCA4_HUMAN (240-795): 9.37e-11: 70.1: 8.98
+	Mm
		818702 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		SMCA4_MOUSE (215-795): 2.11e-13: 79: 8.94
+	Mm
		1111947 NSD2_MOUSE (10-255): 7.97e-34: 133: 11.16		SMCA4_MOUSE (215-795): 2.11e-13: 79: 8.94
+	Hs
		818785 SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57		SMCA4_HUMAN (240-795): 9.37e-11: 70.1: 8.98