HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: FOXP4 (Q8IVH2)
Forkhead box protein P4 (Fork head-related protein-like A)
Gene: FOXP4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35140242, 23667531
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 680
+	Hs
		727774 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		FOXP4_HUMAN (1-669): 0: 599: 100.00
+	Hs
		818461 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		FOXP1_HUMAN (1-679): 1.33e-169: 503: 54.38
+	Hs
		1217570 SOX13_HUMAN (29-192): 1.22e-34: 134: 28.05		FOXP4_HUMAN (1-669): 0: 599: 100.00
+	Hs
		727803 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		FOXP1_HUMAN (1-679): 1.33e-169: 503: 54.38
+	Hs
		1329974 SOX13_HUMAN (29-192): 1.22e-34: 134: 28.05		FOXP1_HUMAN (1-679): 1.33e-169: 503: 54.38
+	Hs
		178952 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		FOXP2_HUMAN (201-679): 3.18e-130: 402: 58.75
+	Hs
		178995 SOX13_HUMAN (29-192): 1.22e-34: 134: 28.05		FOXP2_HUMAN (201-679): 3.18e-130: 402: 58.75
+	Hs
		817928 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		FOXK2_HUMAN (373-646): 2.42e-50: 187: 24.91
+	Hs
		817922 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		FOXK1_HUMAN (363-657): 1.5e-47: 180: 23.03
+	Hs
		993347 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		FOXM1_HUMAN (246-679): 4.79e-62: 222: 20.13
+	Hs
		727724 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		FOXK1_HUMAN (363-657): 1.5e-47: 180: 23.03
+	Hs
		1021259 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		FOXI1_HUMAN (386-680): 2.72e-49: 178: 20.86
+	Hs
		817993 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		FOXC1_HUMAN (466-543): 4.66e-12: 70.9: 43.37
+	Hs
		1318644 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		FOXQ1_HUMAN (371-664): 5.99e-47: 172: 17.28
+	Dm
		115537 M9PFG6_DROME (21-121): 2.56e-40: 147: 78.22		CROC_DROME (466-580): 1.79e-41: 160: 33.33
+	Dm
		685356 Q59DN5_DROME (12-127): 3.31e-39: 147: 42.24		CROC_DROME (466-580): 1.79e-41: 160: 33.33
+	Hs
		1021354 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		FOXL1_HUMAN (421-654): 3.78e-43: 160: 25.70
+	Hs
		1021357 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		FOXL1_HUMAN (421-654): 3.78e-43: 160: 25.70
+	Hs
		727739 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		FOXC1_HUMAN (466-543): 4.66e-12: 70.9: 43.37
+	Hs
		1021167 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		FOXC1_HUMAN (466-543): 4.66e-12: 70.9: 43.37