HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: GCN1 (Q92616)
Stalled ribosome sensor GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)
Gene: GCN1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34732716, 23667531
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 2671
+	Hs
		818325 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		TNPO1_HUMAN (908-1705): 1.2e-50: 198: 13.59
+	Hs
		127215 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		IPO5_HUMAN (1381-2409): 4.59e-37: 155: 12.18
+	Hs
		268831 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		SF3B1_HUMAN (1238-2069): 1.02e-61: 236: 13.97
+	Hs
		818211 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		CAND1_HUMAN (1460-2587): 2.11e-22: 108: 13.92
+	Hs
		818033 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		CKAP5_HUMAN (953-1968): 8.99e-11: 70.1: 10.33
+	Hs
		672409 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		2AAB_HUMAN (2265-2670): 2.67e-36: 149: 14.67
+	Hs
		996747 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		CAND1_HUMAN (1460-2587): 2.11e-22: 108: 13.92
+	Hs
		672251 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		2AAA_HUMAN (959-1405): 1.51e-19: 97.8: 12.22