HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: USP9X (Q93008)
Ubiquitin carboxyl-terminal hydrolase 9X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)
Gene: USP9X

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	31605775, 23667531
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 2554
+	Hs
		818615 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		UBP24_HUMAN (36-2478): 0: 2211: 29.78
+	Hs
		818328 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		818449 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		UBP44_HUMAN (1445-1988): 6.23e-99: 338: 17.63
+	Hs
		818180 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		UBP34_HUMAN (221-474): 1.84e-77: 290: 25.19
+	Mm
		981839 SOX9_MOUSE (28-260): 2.1e-38: 144: 27.98		UBP7_MOUSE (1469-2119): 1.12e-95: 339: 18.82
+	Hs
		818831 SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		1273902 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		1273811 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		727904 SOX6_HUMAN (29-244): 2.42e-29: 120: 23.61		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82