HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: ATAD5 (Q96QE3)
ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein)
Gene: ATAD5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 1844
+	Hs
		818155 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		NIPBL_HUMAN (66-837): 6.64e-54: 211: 12.10
+	Hs
		722188 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77
+	Mm
		725345 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		RFC1_MOUSE (434-1276): 8.02e-54: 209: 14.70
+	Hs
		818382 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		MINT_HUMAN (11-1047): 1.47e-21: 105: 9.24
+	Mm
		725346 SOX17_MOUSE (7-290): 2.02e-35: 134: 27.59		RFC1_MOUSE (434-1276): 8.02e-54: 209: 14.70
+	Hs
		722283 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77
+	Hs
		996715 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		NIPBL_HUMAN (66-837): 6.64e-54: 211: 12.10
+	Hs
		722225 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		RFC1_HUMAN (433-1276): 4.59e-53: 207: 14.77
+	Hs
		817913 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		MAP1A_HUMAN (6-1227): 4.21e-11: 70.7: 7.00
+	Hs
		1056996 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		MDC1_HUMAN (10-849): 1.46e-20: 101: 8.33
+	Hs
		331812 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		MDC1_HUMAN (10-849): 1.46e-20: 101: 8.33
+	Hs
		802428 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		ATRX_HUMAN (88-1036): 2.62e-11: 71.5: 13.08
+	Hs
		331741 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		ATRX_HUMAN (88-1036): 2.62e-11: 71.5: 13.08