HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: WDR26 (Q9H7D7)
WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2)
Gene: WDR26

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28794006, 23667531
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 661
+	Hs
		245575 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		817868 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		245569 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		818834 SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		245636 SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		1281404 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		245585 SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		1281409 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		245594 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		881823 SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		996813 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		FBXW7_HUMAN (314-594): 9.42e-60: 214: 14.53
+	Hs
		818610 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		WDR3_HUMAN (538-660): 2.95e-20: 97.9: 17.89
+	Hs
		1074805 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		TAF5_HUMAN (450-661): 8.05e-55: 202: 14.58
+	Hs
		989530 SOX4_HUMAN (9-289): 2.6e-33: 129: 26.69		TAF5_HUMAN (450-661): 8.05e-55: 202: 14.58
+	Hs
		1103013 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		SMU1_HUMAN (477-661): 1.05e-44: 169: 17.41
+	Hs
		903450 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		903169 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		1343267 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		WDR3_HUMAN (538-660): 2.95e-20: 97.9: 17.89
+	Hs
		1288324 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		SNR40_HUMAN (17-381): 1.88e-13: 74.4: 13.39
+	Hs
		133757 SOX1_HUMAN (4-317): 5.56e-33: 127: 44.76		CIAO1_HUMAN (359-641): 1.55e-15: 80.5: 26.18