HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: LHX9 (Q9NQ69)
LIM/homeobox protein Lhx9 (LIM homeobox protein 9)
Gene: LHX9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0030182 - neuron differentiation
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 397
+	Hs
		474066 UBFL1_HUMAN (20-249): 9.87e-38: 140: 13.39		LHX9_HUMAN (1-397): 9.58e-100: 303: 100.00
+	Hs
		474047 UBFL1_HUMAN (20-249): 9.87e-38: 140: 13.39		LHX2_HUMAN (23-397): 7.27e-78: 248: 60.55
+	Hs
		839810 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		LHX2_HUMAN (23-397): 7.27e-78: 248: 60.55
+	Hs
		822683 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		LHX1_HUMAN (71-396): 6.92e-59: 198: 28.83
+	Dm
		1098042 DICH_DROME (41-117): 1.19e-33: 129: 88.31		Q9V472_DROME (52-392): 8.88e-57: 195: 21.89
+	Hs
		1301002 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		LHX6_HUMAN (17-383): 9.7e-51: 175: 26.43
+	Hs
		818332 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		ISL2_HUMAN (53-125): 6.05e-10: 62.4: 18.92
+	Ce
		447557 EGL13_CAEEL (8-178): 7.66e-34: 130: 35.09		MEC3_CAEEL (64-344): 5.24e-50: 172: 24.47
+	Hs
		638483 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		RBTN1_HUMAN (56-191): 8.64e-40: 140: 43.97
+	Hs
		727819 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		LHX3_HUMAN (131-393): 1.86e-35: 136: 18.63
+	Hs
		638579 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		RBTN1_HUMAN (56-191): 8.64e-40: 140: 43.97
+	Hs
		474068 UBFL1_HUMAN (20-249): 9.87e-38: 140: 13.39		LHX3_HUMAN (131-393): 1.86e-35: 136: 18.63
+	Hs
		1300973 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		LHX3_HUMAN (131-393): 1.86e-35: 136: 18.63
+	Hs
		881817 SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42		LMO3_HUMAN (71-199): 8.86e-38: 135: 44.28
+	Hs
		1281169 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		LHX4_HUMAN (131-356): 2.18e-32: 127: 20.80
+	Hs
		238117 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		LMX1B_HUMAN (15-127): 1.11e-10: 64.7: 20.18