HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: PRR12 (Q9ULL5)
Proline-rich protein 12
Gene: PRR12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28794006, 35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 2036
+	Hs
		818847 SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57		PRR12_HUMAN (1-2036): 7.02e-180: 602: 100.00
+	Hs
		1332330 SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19		PRR12_HUMAN (1-2036): 7.02e-180: 602: 100.00
+	Hs
		1311940 SOX7_HUMAN (23-299): 8.76e-34: 129: 27.03		PRR12_HUMAN (1-2036): 7.02e-180: 602: 100.00
+	Hs
		818101 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		QSER1_HUMAN (298-2030): 2.6e-51: 202: 13.43
+	Hs
		727752 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		QSER1_HUMAN (298-2030): 2.6e-51: 202: 13.43
+	Mm
		101612 Q60I23_MOUSE (1-317): 7.89e-75: 234: 96.24		F8VQL9_MOUSE (331-1876): 7.95e-20: 99.5: 10.09
+	Hs
		818049 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		NCOA6_HUMAN (171-1295): 3.55e-16: 87.6: 8.34
+	Hs
		818266 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		KMT2C_HUMAN (1353-1854): 1.66e-11: 72.4: 11.92
+	Hs
		818373 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		CIC_HUMAN (29-608): 2.88e-11: 71.4: 9.14
+	Hs
		727788 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		CIC_HUMAN (29-608): 2.88e-11: 71.4: 9.14
+	Hs
		818804 SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57		NCOA6_HUMAN (171-1295): 3.55e-16: 87.6: 8.34
+	Hs
		1056996 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		MDC1_HUMAN (92-963): 7.61e-17: 89.7: 11.38
+	Hs
		1057795 SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19		NCOA6_HUMAN (171-1295): 3.55e-16: 87.6: 8.34
+	Hs
		818819 SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57		KMT2C_HUMAN (1353-1854): 1.66e-11: 72.4: 11.92
+	Hs
		818837 SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57		CIC_HUMAN (29-608): 2.88e-11: 71.4: 9.14
+	Hs
		1243843 SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19		KMT2C_HUMAN (1353-1854): 1.66e-11: 72.4: 11.92
+	Hs
		1300941 SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19		CIC_HUMAN (29-608): 2.88e-11: 71.4: 9.14
+	Hs
		1243837 SOX7_HUMAN (23-299): 8.76e-34: 129: 27.03		KMT2C_HUMAN (1353-1854): 1.66e-11: 72.4: 11.92
+	Hs
		881826 SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42		CIC_HUMAN (29-608): 2.88e-11: 71.4: 9.14
+	Hs
		577685 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		SON_HUMAN (1329-1560): 2.13e-09: 65.2: 23.14