HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: WDR3 (Q9UNX4)
WD repeat-containing protein 3
Gene: WDR3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23667531
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 943
+	Hs
		1343267 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		WDR3_HUMAN (1-943): 0: 650: 100.00
+	Hs
		817868 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Hs
		818441 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		TBL1R_HUMAN (3-138): 9.77e-27: 117: 17.93
+	Hs
		254063 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		WDR1_HUMAN (603-905): 7.64e-26: 115: 10.00
+	Mm
		1142008 Q60I23_MOUSE (1-317): 7.89e-75: 234: 96.24		TBL1R_MOUSE (3-138): 8.23e-27: 117: 17.93
+	Hs
		818286 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		UTP15_HUMAN (218-514): 4.75e-22: 103: 12.67
+	Hs
		817979 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		TBL3_HUMAN (4-93): 1.78e-17: 89.6: 13.33
+	Hs
		903450 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Hs
		903169 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Hs
		903155 SRY_HUMAN (30-200): 2.26e-32: 120: 39.18		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Hs
		818834 SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57		FBXW7_HUMAN (35-172): 1.4e-24: 112: 17.69
+	Hs
		1281404 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		FBXW7_HUMAN (35-172): 1.4e-24: 112: 17.69
+	Hs
		1281409 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		FBXW7_HUMAN (35-172): 1.4e-24: 112: 17.69
+	Hs
		881823 SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42		FBXW7_HUMAN (35-172): 1.4e-24: 112: 17.69
+	Hs
		996881 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		TBL1R_HUMAN (3-138): 9.77e-27: 117: 17.93
+	Hs
		996813 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		FBXW7_HUMAN (35-172): 1.4e-24: 112: 17.69
+	Ce
		1089274 SOX2_CAEEL (7-251): 2.45e-32: 123: 38.78		WDR51_CAEEL (1-92): 2.51e-15: 80.7: 15.46
+	Hs
		996886 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		SKI8_HUMAN (486-703): 8.04e-10: 63.2: 25.56
+	Hs
		996930 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		NLE1_HUMAN (748-843): 7.27e-09: 61.4: 4.12