HitPredict

Interactor 1: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: PAX6 (P63015)
Paired box protein Pax-6 (Oculorhombin)
Gene: PAX6

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 20211142
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 23 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 319
Mm

1 422
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024