HitPredict

Interactor 1: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: Q6P5E3 (Q6P5E3)
Sal-like 1 (Drosophila) (Spalt like transcription factor 1)
Gene: Sall1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31077711
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 319 Mm			1 1323
+	Mm
		1142017 Q60I23_MOUSE (1-319): 1.52e-65: 210: 98.43		SALL1_MOUSE (1-1323): 0: 763: 99.55
+	Hs
		818504 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		SALL1_HUMAN (1-1323): 0: 720: 89.60
+	Mm
		1207356 NSD2_MOUSE (5-254): 5.58e-31: 125: 11.92		SALL1_MOUSE (1-1323): 0: 763: 99.55
+	Mm
		1142002 Q60I23_MOUSE (1-319): 1.52e-65: 210: 98.43		SALL3_MOUSE (1-1320): 0: 677: 47.17
+	Mm
		1160032 NSD2_MOUSE (5-254): 5.58e-31: 125: 11.92		Q6P5E3_MOUSE (1-1323): 0: 756: 100.00
+	Hs
		1300959 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		SALL1_HUMAN (1-1323): 0: 720: 89.60
+	Hs
		818425 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		SALL3_HUMAN (1-1320): 0: 639: 44.39
+	Hs
		1311934 SOX7_HUMAN (2-276): 1.14e-27: 112: 25.87		SALL1_HUMAN (1-1323): 0: 720: 89.60
+	Hs
		1332324 SOX17_HUMAN (17-285): 2.31e-27: 112: 26.37		SALL1_HUMAN (1-1323): 0: 720: 89.60
+	Hs
		1300976 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		ZN629_HUMAN (1025-1321): 2.02e-105: 356: 16.07
+	Hs
		727911 SOX6_HUMAN (18-245): 1.28e-28: 117: 24.14		ZN184_HUMAN (3-443): 1e-112: 373: 7.73
+	Hs
		996776 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		ZFP62_HUMAN (4-356): 5.59e-74: 267: 7.95
+	Mm
		1142020 Q60I23_MOUSE (1-319): 1.52e-65: 210: 98.43		SALL2_MOUSE (1130-1315): 1.15e-14: 81.5: 25.82
+	Hs
		818650 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		SALL2_HUMAN (1130-1315): 3.98e-15: 83: 26.76
+	Mm
		818739 SOX2_MOUSE (1-319): 3.85e-64: 207: 100.00		SALL4_MOUSE (1106-1214): 1.19e-11: 71.5: 24.78
+	Mm
		1207350 NSD2_MOUSE (5-254): 5.58e-31: 125: 11.92		SALL4_MOUSE (1106-1214): 1.19e-11: 71.5: 24.78
+	Hs
		474063 UBFL1_HUMAN (15-269): 1.35e-29: 118: 11.11		ZN558_HUMAN (704-787): 2.81e-09: 62.8: 36.91
+	Ce
		107525 EGL13_CAEEL (15-180): 1.54e-27: 113: 35.50		SEM4_CAEEL (990-1058): 5.82e-09: 62.8: 44.93