HitPredict

Interactor 1: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: Q8BTS0 (Q8BTS0)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5)
Gene: Ddx5

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31077711
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 319 Mm			1 615
+	Hs
		571352 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		DDX5_HUMAN (1-615): 0: 609: 98.86
+	Hs
		571557 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		DDX5_HUMAN (1-615): 0: 609: 98.86
+	Hs
		571415 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		DDX5_HUMAN (1-615): 0: 609: 98.86
+	Mm
		818707 SOX2_MOUSE (1-319): 3.85e-64: 207: 100.00		DDX17_MOUSE (30-613): 0: 529: 67.37
+	Hs
		818320 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		DDX17_HUMAN (30-613): 2.43e-179: 527: 67.54
+	Hs
		1271630 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		DDX17_HUMAN (30-613): 2.43e-179: 527: 67.54
+	Hs
		996809 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		DDX17_HUMAN (30-613): 2.43e-179: 527: 67.54
+	Hs
		133924 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		DDX3X_HUMAN (3-478): 1.97e-148: 445: 38.66
+	Hs
		134175 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		DDX3X_HUMAN (3-478): 1.97e-148: 445: 38.66
+	Hs
		996752 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		DDX42_HUMAN (7-614): 2.05e-154: 469: 33.92
+	Dm
		580724 HMG2_DROME (29-138): 5.13e-13: 70.9: 15.18		DDX17_DROME (5-481): 2.29e-150: 452: 60.96
+	Hs
		331834 NSD2_HUMAN (1-288): 5.77e-29: 119: 11.04		DDX46_HUMAN (50-477): 2.27e-108: 351: 40.68