HitPredict

Interactor 1: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: PRP19 (Q99KP6)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: Prpf19

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31077711
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 319 Mm			1 504
+	Hs
		818603 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		PRP19_HUMAN (1-504): 1.34e-163: 474: 99.41
+	Hs
		1300998 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		PRP19_HUMAN (1-504): 1.34e-163: 474: 99.41
+	Hs
		996957 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		PRP19_HUMAN (1-504): 1.34e-163: 474: 99.41
+	Hs
		818834 SOX9_HUMAN (27-262): 1.46e-38: 144: 27.24		FBXW7_HUMAN (67-498): 6.11e-80: 265: 17.15
+	Hs
		996930 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		NLE1_HUMAN (110-504): 6.21e-87: 277: 18.39
+	Hs
		1281409 TF7L2_HUMAN (46-269): 1.49e-35: 137: 17.78		FBXW7_HUMAN (67-498): 6.11e-80: 265: 17.15
+	Hs
		881823 SOX10_HUMAN (27-221): 3.97e-35: 134: 34.36		FBXW7_HUMAN (67-498): 6.11e-80: 265: 17.15
+	Hs
		996813 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		FBXW7_HUMAN (67-498): 6.11e-80: 265: 17.15
+	Hs
		1281404 HM20A_HUMAN (1-248): 4.57e-34: 129: 12.35		FBXW7_HUMAN (67-498): 6.11e-80: 265: 17.15
+	Hs
		196970 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		PRP4_HUMAN (306-504): 7.64e-49: 177: 18.66
+	Hs
		817868 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		WDR5_HUMAN (55-333): 1.74e-46: 166: 14.83
+	Hs
		903450 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		WDR5_HUMAN (55-333): 1.74e-46: 166: 14.83
+	Hs
		197008 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		PRP4_HUMAN (306-504): 7.64e-49: 177: 18.66
+	Hs
		903169 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		WDR5_HUMAN (55-333): 1.74e-46: 166: 14.83
+	Hs
		209427 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		PLRG1_HUMAN (348-504): 5.39e-42: 158: 22.01
+	Hs
		1074805 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		TAF5_HUMAN (233-434): 9.56e-17: 85.5: 27.09
+	Hs
		996824 SSRP1_HUMAN (21-205): 1.2e-33: 132: 15.14		SNR40_HUMAN (82-290): 5.28e-23: 102: 16.36
+	Hs
		1288324 HM20A_HUMAN (1-248): 4.57e-34: 129: 12.35		SNR40_HUMAN (82-290): 5.28e-23: 102: 16.36
+	Hs
		331862 NSD2_HUMAN (1-288): 5.77e-29: 119: 11.04		SNR40_HUMAN (82-290): 5.28e-23: 102: 16.36
+	Hs
		989530 SOX4_HUMAN (3-291): 7.9e-28: 114: 25.08		TAF5_HUMAN (233-434): 9.56e-17: 85.5: 27.09