Interactor 1: RXRG (P48443)
Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma)
Gene: RXRG

Interactor 2: NR1H3 (Q13133)
Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3)
Gene: NR1H3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 25416956, 25910212, 21516116, 32296183, 15604093, 31515488, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid bait and prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0004879 - nuclear receptor activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 463
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024