HitPredict

Interactor 1: PP2BB (P48453)
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit beta isoform) (CNA beta)
Gene: Ppp3cb

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	28671696, 28469556
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0044877 - protein-containing complex binding GO:0098978 - glutamatergic synapse
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 525 Mm			1 1730
+	Mm
		930605 PP2BA_MOUSE (13-524): 0: 853: 83.63		SHAN3_MOUSE (1-1730): 0: 626: 100.00
+	Hs
		994123 PP2BA_HUMAN (13-524): 0: 855: 84.02		SHAN2_HUMAN (8-1727): 2.64e-135: 466: 40.52
+	Mm
		926540 PP1G_MOUSE (48-354): 7.49e-173: 492: 35.87		SHAN3_MOUSE (1-1730): 0: 626: 100.00
+	Mm
		930628 PP2AA_MOUSE (51-347): 1.04e-171: 488: 40.80		SHAN3_MOUSE (1-1730): 0: 626: 100.00
+	Hs
		738019 PP1G_HUMAN (48-354): 7.99e-173: 491: 35.87		SHAN3_HUMAN (1-1730): 0: 601: 95.21
+	Hs
		862021 PP2AA_HUMAN (51-347): 1.04e-171: 488: 40.80		DAPK1_HUMAN (17-450): 1.03e-87: 318: 15.97
+	Hs
		906005 PP1A_HUMAN (61-346): 1.48e-172: 491: 37.28		MIB1_HUMAN (187-625): 7.14e-50: 195: 10.66
+	Hs
		905838 PP1A_HUMAN (61-346): 1.48e-172: 491: 37.28		ANK2_HUMAN (212-349): 7.67e-29: 129: 24.64