HitPredict

Interactor 1: PP2BC (P48454)
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin, testis-specific catalytic subunit) (Calmodulin-dependent calcineurin A subunit gamma isoform)
Gene: PPP3CC

Interactor 2: CRTC2 (Q53ET0)
CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2)
Gene: CRTC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 693
+	Hs
		994087 PP2BA_HUMAN (6-512): 0: 826: 80.59		CRTC2_HUMAN (1-693): 1.02e-75: 259: 100.00
+	Mm
		930603 PP2BA_MOUSE (6-512): 0: 824: 80.39		CRTC2_MOUSE (1-693): 4.4e-68: 238: 92.08
+	Hs
		557551 PP2BB_HUMAN (12-504): 0: 793: 82.66		CRTC2_HUMAN (1-693): 1.02e-75: 259: 100.00
+	Hs
		819177 PP2BC_HUMAN (1-512): 0: 844: 100.00		CIC_HUMAN (88-691): 4e-09: 62.2: 9.81
+	Rn
		930617 PP2BA_RAT (6-512): 0: 824: 80.39		SYNJ1_RAT (1-424): 3.41e-11: 69.1: 12.44
+	Hs
		302276 PP1A_HUMAN (33-333): 8.53e-171: 486: 35.48		SC31A_HUMAN (256-576): 2.89e-10: 66: 14.86
+	Hs
		90115 PP1A_HUMAN (33-333): 8.53e-171: 486: 35.48		D6REX3_HUMAN (153-530): 3.52e-09: 62.5: 13.23
+	Hs
		737992 PP1G_HUMAN (33-347): 7.16e-171: 486: 35.60		CIC_HUMAN (88-691): 4e-09: 62.2: 9.81
+	Hs
		906093 PP1A_HUMAN (33-333): 8.53e-171: 486: 35.48		CIC_HUMAN (88-691): 4e-09: 62.2: 9.81
+	Hs
		905998 PP1A_HUMAN (33-333): 8.53e-171: 486: 35.48		BCL9L_HUMAN (91-672): 9.23e-09: 61: 9.11
+	Hs
		915264 PP2AB_HUMAN (38-334): 4.61e-170: 483: 39.80		CIC_HUMAN (88-691): 4e-09: 62.2: 9.81