HitPredict - High confidence protein-protein interactions

Interactor 1: INAR2 (P48551)
Interferon alpha/beta receptor 2 (IFN-R-2) (IFN-alpha binding protein) (IFN-alpha/beta receptor 2) (Interferon alpha binding protein) (Type I interferon receptor 2)
Gene: IFNAR2

Interactor 2: INAR2 (P48551)
Interferon alpha/beta receptor 2 (IFN-R-2) (IFN-alpha binding protein) (IFN-alpha/beta receptor 2) (Interferon alpha binding protein) (Type I interferon receptor 2)
Gene: IFNAR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.90	0.728

Property	Details
Experiments	17923090, 22807449
Identification Methods	affinity chromatography technology, electrophoretic mobility-based method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Interfer-bind~Interfer-bind, Interfer-bind~Tissue_fac, Tissue_fac~Tissue_fac
Common GO terms	GO:0004905 - type I interferon receptor activity GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0007166 - cell surface receptor signaling pathway and 13 others more... GO:0007259 - cell surface receptor signaling pathway via JAK-STAT GO:0008269 - JAK pathway signal transduction adaptor activity GO:0009615 - response to virus GO:0019901 - protein kinase binding GO:0019955 - cytokine binding GO:0019962 - type I interferon binding GO:0035455 - response to interferon-alpha GO:0035456 - response to interferon-beta GO:0035458 - cellular response to interferon-beta GO:0042018 - interleukin-22 receptor activity GO:0051607 - defense response to virus GO:0060337 - type I interferon-mediated signaling pathway GO:0098586 - cellular response to virus
Homologous interactions	0

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Last updated: 15 Jul 2024