HitPredict

Interactor 1: NRIP1 (P48552)
Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140)
Gene: NRIP1

Interactor 2: Q58EY0 (Q58EY0)
RAR related orphan receptor B isoform 1 (RAR-related orphan receptor B) (cDNA, FLJ93970, Homo sapiens RAR-related orphan receptor B (RORB), mRNA)
Gene: RORB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.613

Property	Details
Experiments	35914814, 15604093
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1158 Hs			1 459
+	Hs
		819599 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		NR2C2_HUMAN (1-447): 1.02e-99: 312: 18.75
+	Hs
		130319 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		NR5A2_HUMAN (3-446): 6.54e-99: 308: 23.98
+	Hs
		525293 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		NR2C1_HUMAN (9-447): 5.38e-89: 284: 21.83
+	Hs
		819605 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		NR1H2_HUMAN (7-453): 2.28e-87: 276: 19.91
+	Mm
		1119769 NRIP1_MOUSE (1-1158): 0: 2078: 84.34		NR2C1_MOUSE (9-447): 2.25e-93: 295: 21.67
+	Hs
		819624 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		STF1_HUMAN (3-447): 7.13e-82: 262: 21.55
+	Hs
		509921 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		VDR_HUMAN (3-453): 6.64e-82: 261: 21.44
+	Hs
		500358 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		RARB_HUMAN (9-138): 6.04e-46: 167: 42.31
+	Hs
		740463 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		PPARG_HUMAN (8-128): 1.04e-45: 167: 46.34
+	Hs
		487921 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		RARA_HUMAN (9-84): 3.92e-43: 159: 61.84
+	Mm
		509330 NRIP1_MOUSE (1-1158): 0: 2078: 84.34		RARA_MOUSE (9-84): 6.39e-43: 159: 61.84
+	Hs
		587137 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		RXRA_HUMAN (10-91): 4.41e-28: 117: 57.32
+	Hs
		818866 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		RXRG_HUMAN (10-96): 2.96e-27: 115: 54.02
+	Hs
		659696 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		RXRB_HUMAN (10-90): 5.01e-26: 112: 55.56
+	Hs
		819617 NRIP1_HUMAN (1-1158): 0: 2100: 100.00		PPARA_HUMAN (251-450): 1.74e-17: 86.7: 27.81