HitPredict

Interactor 1: CLA4 (P48562)
Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)
Gene: CLA4

Interactor 2: MYO5 (Q04439)
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)
Gene: MYO5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.807

Property	Details
Experiments	19841731, 14737190
Identification Methods	peptide array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005933 - cellular bud
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 842 Sc			1 1219
+	Sc
		730573 CLA4_YEAST (1-842): 0: 783: 100.00		MYO3_YEAST (1-1205): 0: 1087: 72.08
+	Sc
		976584 STE20_YEAST (98-839): 5.85e-128: 408: 30.92		MYO5_YEAST (1-1219): 0: 1126: 100.00
+	Sc
		730591 STE20_YEAST (98-839): 5.85e-128: 408: 30.92		MYO3_YEAST (1-1205): 0: 1087: 72.08
+	At
		98846 KIN10_ARATH (540-839): 8.95e-123: 381: 25.33		MYO17_ARATH (6-1105): 0: 1111: 27.49
+	Sc
		979586 SKM1_YEAST (63-421): 1.85e-80: 274: 39.55		MYO5_YEAST (1-1219): 0: 1126: 100.00
+	Hs
		522609 STK4_HUMAN (523-838): 2.03e-117: 366: 35.76		MYH7_HUMAN (2-949): 0: 1030: 28.20
+	Hs
		522610 STK3_HUMAN (521-838): 1.35e-115: 362: 34.91		MYH7_HUMAN (2-949): 0: 1030: 28.20
+	Hs
		528408 STK4_HUMAN (523-838): 2.03e-117: 366: 35.76		MYH8_HUMAN (5-830): 0: 1012: 31.37
+	Hs
		528369 STK4_HUMAN (523-838): 2.03e-117: 366: 35.76		MYH6_HUMAN (5-830): 0: 1008: 30.73
+	Hs
		528409 STK3_HUMAN (521-838): 1.35e-115: 362: 34.91		MYH8_HUMAN (5-830): 0: 1012: 31.37
+	Hs
		1023137 STK4_HUMAN (523-838): 2.03e-117: 366: 35.76		MYH2_HUMAN (5-830): 0: 1006: 31.42
+	Hs
		528371 STK3_HUMAN (521-838): 1.35e-115: 362: 34.91		MYH6_HUMAN (5-830): 0: 1008: 30.73
+	Hs
		1027452 STK3_HUMAN (521-838): 1.35e-115: 362: 34.91		MYH2_HUMAN (5-830): 0: 1006: 31.42
+	Hs
		522545 STK4_HUMAN (523-838): 2.03e-117: 366: 35.76		MYH1_HUMAN (5-830): 0: 1002: 30.57
+	Hs
		522546 STK3_HUMAN (521-838): 1.35e-115: 362: 34.91		MYH1_HUMAN (5-830): 0: 1002: 30.57
+	Hs
		725152 PAK2_HUMAN (97-270): 1.23e-30: 129: 21.84		MYH10_HUMAN (2-1099): 0: 1013: 24.07
+	Hs
		117580 KPCA_HUMAN (279-840): 3.6e-119: 377: 18.36		MYO1C_HUMAN (31-736): 0: 570: 41.82
+	Hs
		117684 STK3_HUMAN (521-838): 1.35e-115: 362: 34.91		MYO1C_HUMAN (31-736): 0: 570: 41.82
+	Hs
		214695 AKT3_HUMAN (486-840): 6.13e-118: 368: 22.59		MYO1B_HUMAN (36-730): 5.19e-171: 538: 39.72
+	Hs
		682219 AKT2_HUMAN (427-841): 1.4e-118: 369: 21.88		MYO5A_HUMAN (712-1118): 1.31e-10: 68.2: 9.31