HitPredict

Interactor 1: BRO1 (P48582)
Vacuolar-sorting protein BRO1 (Amino acid sensor-independent protein 6) (BCK1-like resistance to osmotic shock protein 1) (BRO domain-containing protein 1) (Nitrogen permease inactivating protein 3) (Vacuolar protein-sorting-associated protein 31)
Gene: BRO1

Interactor 2: BRO1 (P48582)
Vacuolar-sorting protein BRO1 (Amino acid sensor-independent protein 6) (BCK1-like resistance to osmotic shock protein 1) (BRO domain-containing protein 1) (Nitrogen permease inactivating protein 3) (Vacuolar protein-sorting-associated protein 31)
Gene: BRO1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

The method score is based on:

Property	Details
Experiments	17513562, 22940862
Identification Methods	protein complementation assay, affinity chromatography technology
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	ALIX_LYPXL_bnd~ALIX_LYPXL_bnd, ALIX_LYPXL_bnd~BRO1, BRO1~BRO1
Common GO terms	GO:0005737 - cytoplasm GO:0005768 - endosome GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process GO:0007034 - vacuolar transport and 9 others more... GO:0010008 - endosome membrane GO:0016579 - protein deubiquitination GO:0035800 - deubiquitinase activator activity GO:0036010 - protein localization to endosome GO:0043328 - protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0070676 - intralumenal vesicle formation GO:0072671 - mitochondria-associated ubiquitin-dependent protein catabolic process GO:1903003 - positive regulation of protein deubiquitination GO:1904669 - ATP export
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	844
Sc

1	844

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024