HitPredict

Interactor 1: SPB4 (P48594)
Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2)
Gene: SERPINB4

Interactor 2: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019899 - enzyme binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 2346
+	Hs
		667976 SPB3_HUMAN (1-390): 9.6e-176: 496: 91.80		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Hs
		738769 SPB5_HUMAN (1-390): 1.15e-135: 394: 33.59		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Hs
		397029 PAI2_HUMAN (1-390): 1.73e-157: 451: 41.25		GOGA4_HUMAN (1116-2321): 1.5e-33: 145: 9.39
+	Hs
		738749 SPB5_HUMAN (1-390): 1.15e-135: 394: 33.59		GOGA4_HUMAN (1116-2321): 1.5e-33: 145: 9.39
+	Hs
		551809 SPB12_HUMAN (1-390): 5.43e-146: 421: 47.29		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72
+	Hs
		433171 SPA12_HUMAN (4-390): 3.49e-126: 371: 30.16		LAMB1_HUMAN (342-655): 2.89e-12: 74.7: 24.86