HitPredict

Interactor 1: PRS4 (P48601)
26S proteasome regulatory subunit 4 (P26s4)
Gene: Rpt2

Interactor 2: Q9VCD5 (Q9VCD5)
UV excision repair protein RAD23
Gene: DmelCG10694

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 439 Dm			1 290
+	Rn
		906973 PRS4_RAT (24-439): 8.92e-138: 404: 92.55		RD23B_RAT (1-289): 1.07e-76: 241: 22.41
+	Hs
		872133 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		RD23A_HUMAN (1-289): 5.67e-77: 240: 24.93
+	Rn
		1117333 PRS6B_RAT (49-432): 1.03e-129: 382: 48.18		RD23B_RAT (1-289): 1.07e-76: 241: 22.41
+	Sc
		697104 PRS10_YEAST (9-436): 8.69e-144: 419: 37.82		RAD23_YEAST (1-287): 5.83e-58: 192: 19.30
+	Hs
		906946 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		UBQL1_HUMAN (1-258): 7.41e-55: 188: 15.73
+	At
		1092307 PS10A_ARATH (50-430): 1.65e-163: 467: 41.47		UBQ3_ARATH (1-79): 9.44e-31: 118: 25.32
+	Hs
		906941 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		UBQL2_HUMAN (1-258): 4.56e-50: 176: 14.61
+	At
		1352317 PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43		DSK2A_ARATH (1-248): 1.14e-50: 176: 15.95
+	Sc
		697092 PRS4_YEAST (1-439): 7.64e-131: 386: 70.62		RAD23_YEAST (1-287): 5.83e-58: 192: 19.30
+	Hs
		906929 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		UBQL4_HUMAN (1-252): 1.75e-45: 163: 13.61
+	Dm
		820528 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		Q9VWD9_DROME (1-251): 9.47e-42: 152: 15.00
+	Sc
		477391 PRS10_YEAST (9-436): 8.69e-144: 419: 37.82		UBI4P_YEAST (1-78): 2.29e-29: 116: 26.92
+	At
		1092257 PS10B_ARATH (39-433): 7.28e-143: 415: 41.52		UBQ3_ARATH (1-79): 9.44e-31: 118: 25.32
+	Dm
		186163 PRS8_DROME (60-438): 2.22e-125: 371: 45.71		Q9VWD9_DROME (1-251): 9.47e-42: 152: 15.00
+	At
		1092354 PRS4B_ARATH (1-439): 1.87e-137: 403: 77.88		UBQ3_ARATH (1-79): 9.44e-31: 118: 25.32
+	At
		1092413 PRS4A_ARATH (1-439): 4.1e-137: 402: 77.43		UBQ3_ARATH (1-79): 9.44e-31: 118: 25.32
+	Hs
		906808 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		RL40_HUMAN (1-83): 4.1e-31: 114: 26.51
+	Sc
		477313 PRS4_YEAST (1-439): 7.64e-131: 386: 70.62		UBI4P_YEAST (1-78): 2.29e-29: 116: 26.92
+	Hs
		872248 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		RD23B_HUMAN (1-245): 4.62e-21: 94.1: 18.70
+	At
		1092308 PRS6B_ARATH (37-429): 1.66e-128: 379: 45.29		UBQ3_ARATH (1-79): 9.44e-31: 118: 25.32