HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	16713569
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2157 Hs			1 815
+	Hs
		868534 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		ATX1_HUMAN (1-815): 0: 1349: 100.00
+	Hs
		868594 ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15		ATX1_HUMAN (1-815): 0: 1349: 100.00
+	Hs
		868703 MINT_HUMAN (338-2157): 4.08e-29: 130: 10.26		ATX1_HUMAN (1-815): 0: 1349: 100.00
+	Hs
		868830 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		ATX1_HUMAN (1-815): 0: 1349: 100.00
+	Hs
		868698 CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78		ATX1_HUMAN (1-815): 0: 1349: 100.00
+	Mm
		869085 SRRM2_MOUSE (288-2150): 3.04e-32: 140: 9.90		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		869311 NCOR2_MOUSE (864-2156): 1.52e-15: 85.5: 10.32		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		868942 PRC2C_MOUSE (47-1802): 3.61e-14: 81: 10.06		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		869002 MINT_MOUSE (421-2156): 1.17e-12: 76.4: 9.06		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		869164 CIC_MOUSE (5-679): 2.5e-09: 65.1: 9.49		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Hs
		473485 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15
+	Hs
		473522 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15
+	Hs
		473535 ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15		ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15
+	Hs
		473582 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15
+	Hs
		473553 CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78		ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15