HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: EIF3B (P55884)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)
Gene: EIF3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2157 Hs			1 814
+	Hs
		879264 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		EIF3B_HUMAN (1-814): 0: 830: 100.00
+	Hs
		879366 SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83		EIF3B_HUMAN (1-814): 0: 830: 100.00
+	Hs
		879320 CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78		EIF3B_HUMAN (1-814): 0: 830: 100.00
+	Hs
		820867 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71
+	Hs
		903374 KMT2C_HUMAN (79-2077): 7.51e-50: 199: 10.05		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71
+	Hs
		245652 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		TBL1X_HUMAN (408-730): 4.48e-54: 198: 11.02
+	Hs
		1346970 SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83		NLE1_HUMAN (507-723): 2.49e-34: 139: 17.03
+	Hs
		903354 ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71
+	Mm
		541461 MAP1B_MOUSE (491-2148): 8.51e-41: 168: 8.67		LIS1_MOUSE (231-410): 4.81e-23: 104: 10.73
+	Hs
		1302927 MINT_HUMAN (338-2157): 4.08e-29: 130: 10.26		NLE1_HUMAN (507-723): 2.49e-34: 139: 17.03
+	Hs
		793042 SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83		LIS1_HUMAN (231-410): 5.42e-23: 104: 10.73
+	Hs
		1346974 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		NLE1_HUMAN (507-723): 2.49e-34: 139: 17.03
+	Hs
		1309170 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		TBL1Y_HUMAN (506-729): 1.02e-27: 120: 12.82
+	Hs
		152622 KMT2D_HUMAN (411-984): 1.99e-09: 65.4: 19.37		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71
+	Hs
		903450 CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71
+	Mm
		903669 KMT2C_MOUSE (1247-2156): 9.62e-09: 63.1: 9.45		WDR5_MOUSE (554-729): 7.19e-35: 137: 12.71
+	Hs
		1074805 CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78		TAF5_HUMAN (304-497): 3.2e-13: 75.6: 18.32