HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2157 Hs			1 656
+	Hs
		726649 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		318639 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02
+	Hs
		118565 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		EYA2_HUMAN (27-278): 1.48e-18: 91.3: 20.16
+	Hs
		358497 ANK2_HUMAN (12-1866): 6e-46: 186: 11.09		CO1A1_HUMAN (2-506): 1.09e-18: 92.9: 14.74
+	Hs
		967303 TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		967173 MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		318762 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02
+	Hs
		967541 PCLO_HUMAN (5-2021): 2.81e-09: 65.1: 8.02		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		967374 CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		318703 CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78		EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02
+	Hs
		726817 MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		726873 ZEP3_HUMAN (972-2156): 3.02e-13: 78.2: 8.72		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		118625 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		EYA2_HUMAN (27-278): 1.48e-18: 91.3: 20.16
+	Hs
		118512 KMT2D_HUMAN (411-984): 1.99e-09: 65.4: 19.37		EYA2_HUMAN (27-278): 1.48e-18: 91.3: 20.16
+	Hs
		118599 CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78		EYA2_HUMAN (27-278): 1.48e-18: 91.3: 20.16