HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29395067, 26949739
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2157 Hs			1 632
+	Mm
		729533 PRC2A_MOUSE (1-2157): 6.74e-146: 506: 87.73		FMR1_MOUSE (1-632): 0: 1063: 93.99
+	Hs
		988930 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Mm
		729531 PRC2B_MOUSE (1-1456): 8.51e-56: 217: 26.12		FMR1_MOUSE (1-632): 0: 1063: 93.99
+	Hs
		988992 ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Hs
		311804 TACC2_HUMAN (38-2028): 6.76e-31: 136: 8.37		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Mm
		1186751 PRC2A_MOUSE (1-2157): 6.74e-146: 506: 87.73		Q8BPK8_MOUSE (1-357): 0: 688: 97.76
+	Hs
		820851 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		FXR1_HUMAN (1-334): 0: 604: 73.95
+	Mm
		729608 NCOR2_MOUSE (864-2156): 1.52e-15: 85.5: 10.32		FMR1_MOUSE (1-632): 0: 1063: 93.99
+	Mm
		1142853 PRC2A_MOUSE (1-2157): 6.74e-146: 506: 87.73		FXR1_MOUSE (1-334): 0: 596: 73.65
+	Hs
		843719 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		FXR1_HUMAN (1-334): 0: 604: 73.95
+	Mm
		1186627 PRC2B_MOUSE (1-1456): 8.51e-56: 217: 26.12		Q8BPK8_MOUSE (1-357): 0: 688: 97.76
+	Mm
		1142852 PRC2B_MOUSE (1-1456): 8.51e-56: 217: 26.12		FXR1_MOUSE (1-334): 0: 596: 73.65
+	Mm
		1207112 NCOR2_MOUSE (864-2156): 1.52e-15: 85.5: 10.32		Q8BPK8_MOUSE (1-357): 0: 688: 97.76
+	Hs
		231799 MABP1_HUMAN (320-1044): 3.41e-41: 169: 13.96		FXR1_HUMAN (1-334): 0: 604: 73.95
+	Hs
		843784 ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15		FXR1_HUMAN (1-334): 0: 604: 73.95
+	Hs
		820852 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56
+	Hs
		311796 TACC2_HUMAN (38-2028): 6.76e-31: 136: 8.37		FXR1_HUMAN (1-334): 0: 604: 73.95
+	Mm
		1142913 NCOR2_MOUSE (864-2156): 1.52e-15: 85.5: 10.32		FXR1_MOUSE (1-334): 0: 596: 73.65
+	Hs
		844097 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56
+	Hs
		231800 MABP1_HUMAN (320-1044): 3.41e-41: 169: 13.96		FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56