HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21903422
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2157 Hs			1 446
+	Hs
		1127640 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Hs
		1025604 SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83		CACO2_HUMAN (1-446): 3.19e-64: 215: 100.00
+	Hs
		787897 ANK2_HUMAN (12-1866): 6e-46: 186: 11.09		EPS15_HUMAN (77-234): 4.48e-10: 64: 11.88
+	Hs
		725139 ANK2_HUMAN (12-1866): 6e-46: 186: 11.09		MYH10_HUMAN (60-417): 3.37e-09: 61.3: 12.06
+	Hs
		724782 ANK2_HUMAN (12-1866): 6e-46: 186: 11.09		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05
+	Hs
		1056882 MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Hs
		1201955 PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13		TAXB1_HUMAN (13-437): 1.11e-40: 156: 21.87
+	Hs
		990892 ZO1_HUMAN (265-982): 3.45e-30: 133: 13.23		DLG5_HUMAN (77-439): 7.24e-18: 88.6: 10.03
+	Hs
		724700 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05
+	Hs
		990961 ZO1_HUMAN (265-982): 3.45e-30: 133: 13.23		MRCKB_HUMAN (99-376): 1.32e-09: 62.8: 9.94
+	Hs
		1051385 TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60		DCTN1_HUMAN (104-339): 7.78e-10: 63.2: 10.83
+	Hs
		944678 MAP1A_HUMAN (389-2155): 2.3e-14: 81.6: 8.60		DCTN1_HUMAN (104-339): 7.78e-10: 63.2: 10.83
+	Hs
		1186077 MICA3_HUMAN (508-1148): 4.25e-10: 67.7: 17.71		MY18A_HUMAN (127-365): 3.21e-10: 64.8: 15.81
+	Hs
		724893 MICA3_HUMAN (508-1148): 4.25e-10: 67.7: 17.71		MYH9_HUMAN (144-345): 7.94e-09: 60.2: 15.05
+	Hs
		1300969 CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78		DAPLE_HUMAN (154-345): 5.26e-09: 61: 20.71
+	Rn
		1126747 SYNJ1_RAT (565-1023): 5.95e-09: 63.8: 13.87		Q5JC29_RAT (77-225): 3.69e-09: 60.9: 9.93