HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2157 Hs			1 768
+	Hs
		1042076 KMT2C_HUMAN (79-2077): 7.51e-50: 199: 10.05		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		807715 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042858 SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042166 TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		152641 KMT2D_HUMAN (411-984): 1.99e-09: 65.4: 19.37		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		807716 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043642 SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043127 TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043482 TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1041413 TITIN_HUMAN (25-1264): 8.01e-19: 96.8: 11.60		CUL2_HUMAN (30-768): 0: 672: 26.17