HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36373674
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2157 Hs			1 1101
+	Hs
		807770 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1221841 SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		990882 ZO1_HUMAN (265-982): 3.45e-30: 133: 13.23		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1221669 MINT_HUMAN (338-2157): 4.08e-29: 130: 10.26		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1221882 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1056884 MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1221873 PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1221662 CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		807858 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		SMC4_HUMAN (2-1073): 2.02e-73: 268: 12.37
+	Hs
		1301004 CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78		SMC3_HUMAN (51-1061): 6.65e-82: 293: 13.91
+	Hs
		1056947 MDC1_HUMAN (907-2156): 1.96e-13: 78.7: 10.22		SMC6_HUMAN (9-1069): 7.85e-63: 235: 15.55
+	Hs
		725139 ANK2_HUMAN (12-1866): 6e-46: 186: 11.09		MYH10_HUMAN (114-762): 2.31e-22: 106: 10.60