HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	30021884, 34349018
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2157 Hs			1 126
+	Hs
		820935 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		241475 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		820873 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		821001 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		H2B1A_HUMAN (1-126): 1.15e-47: 151: 84.25
+	Hs
		1127616 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		H2B2F_HUMAN (1-126): 1.7e-55: 170: 99.21
+	Hs
		241550 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		918418 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		707690 KMT2C_HUMAN (79-2077): 7.51e-50: 199: 10.05		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918533 KMT2C_HUMAN (79-2077): 7.51e-50: 199: 10.05		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		617932 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1O_HUMAN (1-126): 2.36e-55: 170: 99.21
+	Hs
		807749 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B2F_HUMAN (1-126): 1.7e-55: 170: 99.21
+	Hs
		420812 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1J_HUMAN (1-126): 7.3e-55: 169: 97.62
+	Hs
		807743 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		807795 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		241473 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		707546 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		807677 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		807658 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1D_HUMAN (1-126): 3.03e-54: 167: 98.41
+	Hs
		807816 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1N_HUMAN (1-126): 3.07e-54: 167: 98.41
+	Hs
		807775 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B3B_HUMAN (1-126): 1.45e-52: 163: 96.03