HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: GBB2 (P62879)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Gene: GNB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 340
+	Hs
		821156 TCPE_HUMAN (1-541): 0: 635: 100.00		GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29
+	Hs
		826605 TCPG_HUMAN (14-540): 0: 572: 33.15		GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00
+	Hs
		826604 TCPG_HUMAN (14-540): 0: 572: 33.15		GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29
+	Hs
		821326 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1B_HUMAN (126-340): 2.42e-64: 212: 20.37
+	Hs
		821355 TCPE_HUMAN (1-541): 0: 635: 100.00		SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39
+	Sc
		579430 TCPE_YEAST (3-540): 0: 582: 59.89		GBB_YEAST (2-340): 5.29e-76: 241: 36.01
+	Hs
		154661 TCPE_HUMAN (1-541): 0: 635: 100.00		GNB5_HUMAN (129-340): 2.36e-44: 158: 20.81
+	Hs
		826784 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1B_HUMAN (126-340): 2.42e-64: 212: 20.37
+	Hs
		821437 TCPE_HUMAN (1-541): 0: 635: 100.00		NLE1_HUMAN (2-124): 8.9e-29: 117: 26.77
+	Hs
		821316 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1A_HUMAN (3-125): 4.59e-25: 106: 16.92
+	Hs
		154662 TCPG_HUMAN (14-540): 0: 572: 33.15		GNB5_HUMAN (129-340): 2.36e-44: 158: 20.81
+	Hs
		154696 TCPH_HUMAN (12-539): 0: 570: 29.64		GNB5_HUMAN (129-340): 2.36e-44: 158: 20.81
+	Hs
		821152 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92
+	Hs
		196971 TCPE_HUMAN (1-541): 0: 635: 100.00		PRP4_HUMAN (51-253): 4.41e-11: 65.9: 24.88
+	Hs
		826772 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1A_HUMAN (3-125): 4.59e-25: 106: 16.92
+	Hs
		792942 TCPG_HUMAN (14-540): 0: 572: 33.15		LIS1_HUMAN (258-340): 1.53e-19: 90.5: 22.89
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92
+	Sc
		744632 TCPE_YEAST (3-540): 0: 582: 59.89		TAF5_YEAST (180-340): 1.96e-11: 67: 23.29
+	Hs
		196973 TCPG_HUMAN (14-540): 0: 572: 33.15		PRP4_HUMAN (51-253): 4.41e-11: 65.9: 24.88