HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	26496610, 28514442, 31980649, 33961781, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 482
+	Hs
		821342 TCPE_HUMAN (1-541): 0: 635: 100.00		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		826651 TCPG_HUMAN (14-540): 0: 572: 33.15		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1038670 TCPH_HUMAN (12-539): 0: 570: 29.64		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		826803 TCPG_HUMAN (14-540): 0: 572: 33.15		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		573251 TCPA_HUMAN (26-541): 0: 545: 32.08		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		573401 TCPA_HUMAN (26-541): 0: 545: 32.08		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		177231 TCPE_HUMAN (1-541): 0: 635: 100.00		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sc
		693029 TCPE_YEAST (3-540): 0: 582: 59.89		RPD3_YEAST (8-421): 0: 580: 61.48
+	Hs
		177233 TCPG_HUMAN (14-540): 0: 572: 33.15		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		177367 TCPH_HUMAN (12-539): 0: 570: 29.64		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sp
		140725 TCPE_SCHPO (4-541): 0: 598: 68.77		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sc
		693035 TCPH_YEAST (7-540): 0: 542: 30.30		RPD3_YEAST (8-421): 0: 580: 61.48
+	Hs
		177188 TCPA_HUMAN (26-541): 0: 545: 32.08		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sp
		140519 TCPG_SCHPO (12-539): 0: 562: 34.21		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sp
		140638 TCPH_SCHPO (7-541): 0: 558: 30.00		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sc
		772905 TCPE_YEAST (3-540): 0: 582: 59.89		HOS2_YEAST (10-411): 2.72e-171: 491: 50.00
+	Hs
		821448 TCPE_HUMAN (1-541): 0: 635: 100.00		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		826927 TCPG_HUMAN (14-540): 0: 572: 33.15		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		1306720 TCPH_HUMAN (12-539): 0: 570: 29.64		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		573514 TCPA_HUMAN (26-541): 0: 545: 32.08		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78