HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: DCA12 (Q5T6F0)
DDB1- and CUL4-associated factor 12 (Centrosome-related protein TCC52) (Testis cancer centrosome-related protein) (WD repeat-containing protein 40A)
Gene: DCAF12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	33961781, 37689310, 36715408
Identification Methods	affinity chromatography technology, proximity labelling technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 541 Hs			1 453
+	Hs
		826699 TCPG_HUMAN (14-540): 0: 572: 33.15		DCA12_HUMAN (1-453): 0: 815: 100.00
+	Hs
		1134071 TCPH_HUMAN (12-539): 0: 570: 29.64		DCA12_HUMAN (1-453): 0: 815: 100.00
+	Hs
		826705 TCPG_HUMAN (14-540): 0: 572: 33.15		DC122_HUMAN (7-453): 0: 745: 64.07
+	Dm
		1366010 Q9VK69_DROME (36-533): 1.12e-109: 338: 41.39		DCA12_DROME (3-452): 0: 607: 39.65