HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: DDB2 (Q92466)
DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2)
Gene: DDB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 427
+	Hs
		821413 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR76_HUMAN (114-412): 2.61e-81: 264: 23.89
+	Hs
		821190 TCPE_HUMAN (1-541): 0: 635: 100.00		ERCC8_HUMAN (114-324): 1.48e-59: 201: 23.21
+	Hs
		821152 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR5_HUMAN (17-270): 4.83e-57: 192: 13.95
+	Hs
		821316 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1A_HUMAN (6-228): 3.78e-46: 165: 11.66
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (142-427): 6.44e-67: 218: 14.53
+	Hs
		826641 TCPG_HUMAN (14-540): 0: 572: 33.15		ERCC8_HUMAN (114-324): 1.48e-59: 201: 23.21
+	Hs
		821326 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1B_HUMAN (15-187): 3.96e-33: 131: 8.67
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (17-270): 4.83e-57: 192: 13.95
+	Hs
		821437 TCPE_HUMAN (1-541): 0: 635: 100.00		NLE1_HUMAN (279-427): 4.77e-30: 123: 16.77
+	Hs
		792942 TCPG_HUMAN (14-540): 0: 572: 33.15		LIS1_HUMAN (5-231): 5.78e-48: 170: 12.20
+	Hs
		821355 TCPE_HUMAN (1-541): 0: 635: 100.00		SNR40_HUMAN (272-427): 1.08e-24: 106: 12.58
+	Hs
		826772 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1A_HUMAN (6-228): 3.78e-46: 165: 11.66
+	Hs
		821387 TCPE_HUMAN (1-541): 0: 635: 100.00		TBL1Y_HUMAN (277-427): 1.56e-18: 89.5: 11.88
+	Hs
		821157 TCPE_HUMAN (1-541): 0: 635: 100.00		GBB2_HUMAN (217-427): 9.72e-19: 88.6: 15.57
+	Hs
		196971 TCPE_HUMAN (1-541): 0: 635: 100.00		PRP4_HUMAN (273-421): 2.01e-16: 83.2: 12.67
+	Sc
		772950 TCPE_YEAST (3-540): 0: 582: 59.89		CMR1_YEAST (98-427): 4.9e-26: 112: 17.49
+	Sc
		772946 TCPE_YEAST (3-540): 0: 582: 59.89		PRP46_YEAST (114-427): 9.01e-19: 89.8: 16.36
+	Hs
		826605 TCPG_HUMAN (14-540): 0: 572: 33.15		GBB2_HUMAN (217-427): 9.72e-19: 88.6: 15.57
+	Hs
		196973 TCPG_HUMAN (14-540): 0: 572: 33.15		PRP4_HUMAN (273-421): 2.01e-16: 83.2: 12.67
+	Sc
		742830 TCPE_YEAST (3-540): 0: 582: 59.89		GBLP_YEAST (123-315): 1.38e-10: 64: 16.34