HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: TCAB1 (Q9BUR4)
Telomerase Cajal body protein 1 (WD repeat-containing protein 79) (WD40 repeat-containing protein antisense to TP53 gene) (WRAP53beta)
Gene: WRAP53

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26496610, 25467444
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:1904851 - positive regulation of establishment of protein localization to telomere
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 548
+	Hs
		826858 TCPG_HUMAN (14-540): 0: 572: 33.15		TCAB1_HUMAN (1-548): 2.69e-107: 333: 98.37
+	Hs
		821387 TCPE_HUMAN (1-541): 0: 635: 100.00		TBL1Y_HUMAN (274-548): 1.31e-49: 180: 15.75
+	Hs
		196971 TCPE_HUMAN (1-541): 0: 635: 100.00		PRP4_HUMAN (305-548): 2.59e-40: 155: 14.74
+	Hs
		821157 TCPE_HUMAN (1-541): 0: 635: 100.00		GBB2_HUMAN (341-546): 6.74e-33: 130: 12.62
+	Hs
		821437 TCPE_HUMAN (1-541): 0: 635: 100.00		NLE1_HUMAN (51-257): 2.3e-27: 117: 11.59
+	Hs
		826848 TCPG_HUMAN (14-540): 0: 572: 33.15		TBL1Y_HUMAN (274-548): 1.31e-49: 180: 15.75
+	Sc
		744632 TCPE_YEAST (3-540): 0: 582: 59.89		TAF5_YEAST (316-534): 2.78e-40: 157: 17.37
+	Hs
		196973 TCPG_HUMAN (14-540): 0: 572: 33.15		PRP4_HUMAN (305-548): 2.59e-40: 155: 14.74
+	Hs
		197078 TCPH_HUMAN (12-539): 0: 570: 29.64		PRP4_HUMAN (305-548): 2.59e-40: 155: 14.74
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (361-541): 2.58e-41: 153: 12.16
+	Hs
		821152 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR5_HUMAN (455-548): 1.44e-18: 88.9: 9.57
+	Hs
		821355 TCPE_HUMAN (1-541): 0: 635: 100.00		SNR40_HUMAN (445-548): 4.84e-18: 87.7: 11.43
+	Hs
		821326 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1B_HUMAN (457-548): 7.7e-16: 82: 11.96
+	Hs
		821316 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1A_HUMAN (99-199): 3.27e-12: 70.4: 6.93
+	Hs
		826605 TCPG_HUMAN (14-540): 0: 572: 33.15		GBB2_HUMAN (341-546): 6.74e-33: 130: 12.62
+	Hs
		792942 TCPG_HUMAN (14-540): 0: 572: 33.15		LIS1_HUMAN (403-544): 1.49e-30: 125: 14.79
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (455-548): 1.44e-18: 88.9: 9.57
+	Hs
		903467 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5_HUMAN (455-548): 1.44e-18: 88.9: 9.57
+	Hs
		826784 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1B_HUMAN (457-548): 7.7e-16: 82: 11.96
+	Hs
		826772 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1A_HUMAN (99-199): 3.27e-12: 70.4: 6.93