HitPredict

Interactor 1: K2C6C (P48668)
Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK-6C) (Cytokeratin-6E) (CK-6E) (Keratin K6h) (Keratin-6C) (K6C) (Type-II keratin Kb12)
Gene: KRT6C

Interactor 2: EFNA4 (P52798)
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)
Gene: EFNA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	23686814
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 564 Hs			1 201
+	Hs
		380584 K2C1_HUMAN (128-494): 2.73e-165: 486: 73.57		EFNA4_HUMAN (1-185): 1.68e-86: 255: 100.00
+	Hs
		380559 K2C1_HUMAN (128-494): 2.73e-165: 486: 73.57		EFNA1_HUMAN (11-162): 3.84e-69: 211: 43.59
+	Hs
		380583 K2C1_HUMAN (128-494): 2.73e-165: 486: 73.57		EFNA3_HUMAN (21-169): 8.45e-61: 191: 42.50
+	Hs
		856412 K2C73_HUMAN (3-548): 1.45e-97: 308: 54.58		EFNA4_HUMAN (1-185): 1.68e-86: 255: 100.00
+	Hs
		380454 K2C6B_HUMAN (1-499): 1.95e-90: 290: 99.00		EFNA4_HUMAN (1-185): 1.68e-86: 255: 100.00
+	Hs
		856361 KRT83_HUMAN (67-547): 1.3e-89: 286: 48.03		EFNA4_HUMAN (1-185): 1.68e-86: 255: 100.00
+	Hs
		856362 KRT85_HUMAN (1-528): 2.32e-89: 286: 47.73		EFNA4_HUMAN (1-185): 1.68e-86: 255: 100.00
+	Hs
		359474 K2C6A_HUMAN (1-499): 5.37e-86: 279: 98.40		EFNA4_HUMAN (1-185): 1.68e-86: 255: 100.00
+	Hs
		531544 K2C5_HUMAN (3-486): 5.94e-85: 277: 77.35		EFNA4_HUMAN (1-185): 1.68e-86: 255: 100.00
+	Hs
		856473 KRT82_HUMAN (41-560): 1.94e-80: 263: 48.08		EFNA4_HUMAN (1-185): 1.68e-86: 255: 100.00
+	Hs
		380444 K2C6B_HUMAN (1-499): 1.95e-90: 290: 99.00		EFNA1_HUMAN (11-162): 3.84e-69: 211: 43.59
+	Hs
		595981 K2C6C_HUMAN (1-499): 5.3e-90: 289: 100.00		EFNA1_HUMAN (11-162): 3.84e-69: 211: 43.59
+	Hs
		359465 K2C6A_HUMAN (1-499): 5.37e-86: 279: 98.40		EFNA1_HUMAN (11-162): 3.84e-69: 211: 43.59
+	Hs
		531533 K2C5_HUMAN (3-486): 5.94e-85: 277: 77.35		EFNA1_HUMAN (11-162): 3.84e-69: 211: 43.59
+	Hs
		380453 K2C6B_HUMAN (1-499): 1.95e-90: 290: 99.00		EFNA3_HUMAN (21-169): 8.45e-61: 191: 42.50
+	Hs
		821644 K2C6C_HUMAN (1-499): 5.3e-90: 289: 100.00		EFNA3_HUMAN (21-169): 8.45e-61: 191: 42.50
+	Hs
		856436 KRT35_HUMAN (47-476): 3.24e-65: 221: 25.12		EFNA4_HUMAN (1-185): 1.68e-86: 255: 100.00
+	Hs
		359473 K2C6A_HUMAN (1-499): 5.37e-86: 279: 98.40		EFNA3_HUMAN (21-169): 8.45e-61: 191: 42.50
+	Hs
		531543 K2C5_HUMAN (3-486): 5.94e-85: 277: 77.35		EFNA3_HUMAN (21-169): 8.45e-61: 191: 42.50
+	Hs
		856320 K2C71_HUMAN (3-557): 3.15e-85: 275: 52.61		EFNA3_HUMAN (21-169): 8.45e-61: 191: 42.50