HitPredict

Interactor 1: LMNA (P48678)
Prelamin-A/C [Cleaved into: Lamin-A/C]
Gene: LMNA

Interactor 2: SUN2 (Q8BJS4)
SUN domain-containing protein 2 (Protein unc-84 homolog B) (Sad1/unc-84 protein-like 2)
Gene: SUN2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	21327095, 16380439, 22349700
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0006998 - nuclear envelope organization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 665 Mm			1 731
+	Hs
		299617 LMNA_HUMAN (1-665): 8.09e-72: 247: 96.10		SUN1_HUMAN (1-729): 0: 828: 32.01
+	Hs
		360515 LMNA_HUMAN (1-665): 8.09e-72: 247: 96.10		SUN2_HUMAN (1-731): 0: 817: 81.26
+	Hs
		299633 LMNB1_HUMAN (12-548): 1.64e-47: 178: 56.69		SUN1_HUMAN (1-729): 0: 828: 32.01
+	Hs
		595461 LMNB1_HUMAN (12-548): 1.64e-47: 178: 56.69		SUN2_HUMAN (1-731): 0: 817: 81.26
+	Ce
		1093935 LMN1_CAEEL (1-539): 5.62e-53: 193: 29.49		UNC84_CAEEL (492-729): 4.87e-78: 273: 33.88
+	Mm
		821739 LMNA_MOUSE (1-665): 1.31e-71: 246: 100.00		SUN1_MOUSE (1-191): 7.95e-48: 184: 20.10
+	Ce
		1093999 LMN1_CAEEL (1-539): 5.62e-53: 193: 29.49		SUN1_CAEEL (350-729): 3.45e-52: 190: 15.73