HitPredict

Interactor 1: NEST (P48681)
Nestin
Gene: NES

Interactor 2: UBR1 (Q8IWV7)
E3 ubiquitin-protein ligase UBR1 (EC 2.3.2.27) (N-recognin-1) (RING-type E3 ubiquitin transferase UBR1) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3-alpha-I)
Gene: UBR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1621 Hs			1 1749
+	Hs
		443638 VIME_HUMAN (8-343): 3.05e-118: 382: 28.32		UBR1_HUMAN (1-1749): 0: 2525: 100.00
+	Hs
		213967 KRT86_HUMAN (6-313): 2.99e-63: 226: 21.34		UBR1_HUMAN (1-1749): 0: 2525: 100.00
+	Hs
		821785 NEST_HUMAN (1-1621): 1.09e-115: 404: 100.00		UBR2_HUMAN (21-1749): 0: 2327: 47.00
+	Hs
		535459 GFAP_HUMAN (8-316): 8.2e-22: 102: 30.35		UBR1_HUMAN (1-1749): 0: 2525: 100.00
+	Hs
		535460 GFAP_HUMAN (8-316): 8.2e-22: 102: 30.35		UBR2_HUMAN (21-1749): 0: 2327: 47.00
+	Hs
		943644 KRT83_HUMAN (6-313): 2.92e-64: 229: 21.34		UBR3_HUMAN (986-1726): 8.48e-85: 311: 20.67