HitPredict

Interactor 1: NEST (P48681)
Nestin
Gene: NES

Interactor 2: RSPRY (Q96DX4)
RING finger and SPRY domain-containing protein 1
Gene: RSPRY1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1621 Hs			1 576
+	Hs
		443716 VIME_HUMAN (8-343): 3.05e-118: 382: 28.32		RSPRY_HUMAN (1-576): 0: 866: 100.00
+	Hs
		535517 GFAP_HUMAN (8-316): 8.2e-22: 102: 30.35		RSPRY_HUMAN (1-576): 0: 866: 100.00
+	Hs
		422256 NFL_HUMAN (7-323): 1.31e-18: 93.6: 27.95		RSPRY_HUMAN (1-576): 0: 866: 100.00
+	Hs
		1081746 AINX_HUMAN (8-317): 2.29e-17: 89.4: 27.59		RSPRY_HUMAN (1-576): 0: 866: 100.00
+	Hs
		422438 NFM_HUMAN (8-333): 4.76e-14: 79.7: 26.21		RSPRY_HUMAN (1-576): 0: 866: 100.00
+	Hs
		962328 CP250_HUMAN (48-1491): 3.97e-42: 172: 11.11		HNRPU_HUMAN (282-510): 1.71e-44: 171: 16.60
+	Hs
		522554 MYH1_HUMAN (549-1583): 5.34e-33: 142: 10.34		RN123_HUMAN (344-496): 1.77e-44: 171: 35.07
+	Mm
		1140521 MYH9_MOUSE (669-1518): 3.07e-31: 136: 9.52		RN123_MOUSE (344-496): 1.52e-44: 172: 35.71
+	Hs
		1061212 NUMA1_HUMAN (818-1473): 5.43e-19: 96.5: 10.02		RANB9_HUMAN (288-489): 2.19e-52: 192: 18.31
+	Hs
		724869 MYH9_HUMAN (729-1459): 1.22e-24: 115: 10.48		RN123_HUMAN (344-496): 1.77e-44: 171: 35.07
+	Hs
		1140879 MYH4_HUMAN (17-755): 1.14e-23: 111: 10.41		RN123_HUMAN (344-496): 1.77e-44: 171: 35.07
+	Hs
		502918 MYH3_HUMAN (771-1429): 7.51e-23: 109: 8.35		RN123_HUMAN (344-496): 1.77e-44: 171: 35.07
+	Hs
		1034639 GOGA4_HUMAN (1-602): 3.69e-15: 83.8: 9.31		ASH2L_HUMAN (264-498): 3.12e-51: 187: 18.38
+	Mm
		93464 MYH1_MOUSE (549-1583): 7.46e-34: 145: 10.24		RYR2_MOUSE (263-493): 7.48e-16: 83.6: 18.99
+	Mm
		93446 AINX_MOUSE (8-317): 1.98e-16: 86.3: 27.27		RYR2_MOUSE (263-493): 7.48e-16: 83.6: 18.99