HitPredict

Interactor 1: NEST (P48681)
Nestin
Gene: NES

Interactor 2: CK5P2 (Q96SN8)
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
Gene: CDK5RAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007420 - brain development
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1621 Hs			1 1893
+	Hs
		409205 K2C8_HUMAN (7-315): 1.79e-122: 395: 23.68		CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00
+	Hs
		1302322 CP250_HUMAN (48-1491): 3.97e-42: 172: 11.11		CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00
+	Hs
		444536 K2C7_HUMAN (7-321): 7.48e-118: 381: 24.70		GOGA4_HUMAN (1-1777): 1.29e-60: 233: 10.50
+	Hs
		408995 K2C8_HUMAN (7-315): 1.79e-122: 395: 23.68		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		443305 VIME_HUMAN (8-343): 3.05e-118: 382: 28.32		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		148526 NEST_HUMAN (1-1621): 1.09e-115: 404: 100.00		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Mm
		589641 VIME_MOUSE (8-343): 4e-117: 379: 28.32		MYOME_MOUSE (25-1161): 4.31e-19: 96.9: 10.90
+	Hs
		408987 K2C8_HUMAN (7-315): 1.79e-122: 395: 23.68		MYH1_HUMAN (884-1666): 1.1e-12: 76.1: 12.50
+	Mm
		589621 VIME_MOUSE (8-343): 4e-117: 379: 28.32		ROCK2_MOUSE (59-667): 1.25e-15: 85.3: 16.61
+	Hs
		148307 VIME_HUMAN (8-343): 3.05e-118: 382: 28.32		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Hs
		531529 K2C5_HUMAN (7-319): 3.83e-86: 296: 20.56		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		359462 K2C6A_HUMAN (6-332): 1.03e-84: 291: 20.82		DESP_HUMAN (35-576): 3.93e-27: 123: 16.16
+	Hs
		724994 CP250_HUMAN (48-1491): 3.97e-42: 172: 11.11		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Zm
		5443 A0A1D6DZK4_MAIZE (304-1529): 3.91e-43: 175: 10.19		A0A1D6DZK4_MAIZE (1238-1875): 6.09e-17: 89.9: 11.56
+	Hs
		528435 MYH8_HUMAN (570-1583): 2.91e-36: 153: 9.58		MYH4_HUMAN (1156-1882): 1.02e-19: 99.2: 11.08
+	Hs
		528432 MYH8_HUMAN (570-1583): 2.91e-36: 153: 9.58		MYH13_HUMAN (50-537): 8.88e-17: 89.3: 13.44
+	Hs
		725097 MYH11_HUMAN (470-1525): 1.94e-33: 143: 10.43		MYH10_HUMAN (1278-1866): 8.19e-15: 83: 11.48
+	Hs
		148466 MYH11_HUMAN (470-1525): 1.94e-33: 143: 10.43		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Mm
		93570 MYH9_MOUSE (669-1518): 3.07e-31: 136: 9.52		DESP_MOUSE (158-701): 1.83e-09: 65.3: 16.82