Interactor 1: KC1A (P48729)
Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1)
Gene: CSNK1A1

Interactor 2: NLRP3 (Q96P20)
NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Angiotensin/vasopressin receptor AII/AVP-like) (Caterpiller protein 1.1) (CLR1.1) (Cold-induced autoinflammatory syndrome 1 protein) (Cryopyrin) (PYRIN-containing APAF1-like protein 1)
Gene: NLRP3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 34615873
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_6~Pkinase, NACHT~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0016020 - membrane
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 337
Hs

1 1036
+ Mm

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Last updated: 15 Jul 2024