Interactor 1: KC1D (P48730)
Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)
Gene: CSNK1D

Interactor 2: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.681

The method score is based on:

Property Details
Experiments 20708156, 16870621, 22976441
Identification Methods enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 415
Hs

1 491
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024