HitPredict

Interactor 1: KC1D (P48730)
Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26)
Gene: CSNK1D

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 32814053, 25500533
Identification Methods two hybrid array, two hybrid pooling approach, protein kinase assay, validated two hybrid
Interaction Type physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005794 - Golgi apparatus
and 9 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 415
Hs

1 2527
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024