Interactor 1: IDHP (P48735)
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
Gene: IDH2

Interactor 2: SIR3 (Q9NTG7)
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3)
Gene: SIRT3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 34271087
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 452
Hs

1 399
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024