HitPredict

Interactor 1: HSP77 (P48741)
Putative heat shock 70 kDa protein 7 (Heat shock 70 kDa protein B) (Heat shock protein family A member 7)
Gene: HSPA7

Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21145461
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 367 Hs			1 81
+	Dm
		505044 HSP7D_DROME (4-367): 0: 588: 75.00		RS27A_DROME (1-77): 3.39e-36: 121: 57.14
+	Hs
		564084 HSP76_HUMAN (1-367): 0: 606: 90.19		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Hs
		474905 HSP7C_HUMAN (4-367): 0: 591: 73.08		UBB_HUMAN (1-76): 2.4e-30: 107: 57.90
+	Hs
		713983 HS71L_HUMAN (1-367): 0: 595: 75.20		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Ce
		450538 HSP1_CAEEL (4-367): 0: 583: 73.97		NEDD8_CAEEL (1-77): 7.56e-34: 112: 87.01
+	Hs
		504136 HSP7C_HUMAN (4-367): 0: 591: 73.08		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00