HitPredict

Interactor 1: LHX1 (P48742)
LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (hLim-1)
Gene: LHX1

Interactor 2: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005667 - transcription regulator complex GO:0009887 - animal organ morphogenesis GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 406 Hs			1 770
+	Hs
		980662 LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95		TLE1_HUMAN (1-770): 0: 594: 100.00
+	Hs
		980633 LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49		TLE1_HUMAN (1-770): 0: 594: 100.00
+	Hs
		839732 LHX2_HUMAN (2-317): 3.11e-51: 178: 26.84		TLE1_HUMAN (1-770): 0: 594: 100.00
+	Hs
		980622 LHX8_HUMAN (3-307): 2.36e-45: 162: 27.36		TLE1_HUMAN (1-770): 0: 594: 100.00
+	Hs
		980912 LHX6_HUMAN (2-259): 1.04e-44: 160: 30.77		TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42
+	Hs
		993635 LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		993530 LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		839735 LHX2_HUMAN (2-317): 3.11e-51: 178: 26.84		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		245624 LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49		TBL1X_HUMAN (569-769): 5.32e-46: 175: 16.51
+	Hs
		638497 RBTN1_HUMAN (3-57): 2.28e-10: 60.7: 22.41		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		1022844 LMO3_HUMAN (4-121): 4.42e-51: 169: 36.59		STRN3_HUMAN (604-768): 2.4e-28: 123: 15.46