HitPredict

Interactor 1: LHX1 (P48742)
LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (hLim-1)
Gene: LHX1

Interactor 2: KMT2C (Q8NEZ4)
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)
Gene: KMT2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 406 Hs			1 4911
+	Hs
		1243849 LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95		KMT2C_HUMAN (1-4911): 0: 2416: 100.00
+	Hs
		1243832 LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49		KMT2C_HUMAN (1-4911): 0: 2416: 100.00
+	Hs
		839785 LHX2_HUMAN (2-317): 3.11e-51: 178: 26.84		KMT2C_HUMAN (1-4911): 0: 2416: 100.00
+	Hs
		822655 LHX1_HUMAN (1-406): 1.12e-95: 293: 100.00		DPF1_HUMAN (350-435): 3.04e-13: 77: 40.45
+	Hs
		152612 LHX1_HUMAN (1-406): 1.12e-95: 293: 100.00		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82
+	Dm
		114766 M9PD53_DROME (1-376): 7.91e-55: 191: 31.10		Q9W1H0_DROME (954-1243): 2.58e-36: 155: 22.77
+	Dm
		112563 M9NCY1_DROME (1-376): 1.87e-55: 189: 31.10		Q9W1H0_DROME (954-1243): 2.58e-36: 155: 22.77
+	Dm
		1368403 Q9VJ37_DROME (1-341): 1.03e-49: 177: 25.99		Q9W1H0_DROME (954-1243): 2.58e-36: 155: 22.77
+	Dm
		954993 P92031_DROME (1-341): 1.24e-49: 177: 25.99		Q9W1H0_DROME (954-1243): 2.58e-36: 155: 22.77
+	Hs
		1270594 LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95		DPF1_HUMAN (350-435): 3.04e-13: 77: 40.45
+	Hs
		1270721 LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95		REQU_HUMAN (359-435): 2.72e-12: 74.3: 41.25
+	Hs
		1270582 LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49		DPF1_HUMAN (350-435): 3.04e-13: 77: 40.45
+	Ce
		589683 LIN11_CAEEL (2-324): 2.02e-56: 192: 42.11		DPFF1_CAEEL (350-447): 6.55e-14: 79: 39.60
+	Hs
		1270662 LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49		REQU_HUMAN (359-435): 2.72e-12: 74.3: 41.25
+	Hs
		152696 LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82
+	Hs
		152677 LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82
+	Hs
		839794 LHX2_HUMAN (2-317): 3.11e-51: 178: 26.84		DPF1_HUMAN (350-435): 3.04e-13: 77: 40.45
+	Hs
		839795 LHX2_HUMAN (2-317): 3.11e-51: 178: 26.84		REQU_HUMAN (359-435): 2.72e-12: 74.3: 41.25
+	Hs
		152615 LHX2_HUMAN (2-317): 3.11e-51: 178: 26.84		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82
+	Hs
		152657 LHX8_HUMAN (3-307): 2.36e-45: 162: 27.36		KMT2D_HUMAN (2766-3637): 7.14e-09: 65: 8.82