HitPredict

Interactor 1: BRCA1 (P48754)
Breast cancer type 1 susceptibility protein homolog (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: BRCA2 (P97929)
Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog)
Gene: BRCA2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.642

The method score is based on:

Property Details
Experiments 20211142, 31242413, 11477095
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000152 - nuclear ubiquitin ligase complex
GO:0000724 - double-strand break repair via homologous recombination
GO:0000800 - lateral element
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 13 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1812
Mm

1 3329
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024