HitPredict

Interactor 1: RB27C (P48809)
Heterogeneous nuclear ribonucleoprotein 27C (Hrb27-C) (HRP48.1) (hnRNP 48)
Gene: Hrb27C

Interactor 2: SQD (Q08473)
RNA-binding protein squid (Heterogeneous nuclear ribonucleoprotein 40) (HNRNP 40)
Gene: SQD

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.891

Property	Details
Experiments	1730753, 18082158, 15056611, 8355684
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0045451 - pole plasm oskar mRNA localization
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 421 Dm			1 344
+	Dm
		432486 RB27C_DROME (1-421): 2.05e-74: 240: 100.00		ROA1_DROME (40-219): 1.42e-72: 231: 35.08
+	Hs
		852054 HNRPD_HUMAN (3-273): 3.96e-53: 182: 27.31		ROA3_HUMAN (49-220): 5.19e-76: 240: 35.52
+	Dm
		432490 ROA1_DROME (2-179): 7.09e-58: 195: 36.67		SQD_DROME (1-218): 2.05e-63: 206: 100.00
+	Hs
		1048197 HNRPD_HUMAN (3-273): 3.96e-53: 182: 27.31		ROAA_HUMAN (34-344): 1.32e-54: 183: 33.54
+	Hs
		162045 HNRPD_HUMAN (3-273): 3.96e-53: 182: 27.31		HNRDL_HUMAN (18-344): 8.21e-53: 181: 33.74
+	Hs
		963520 TIAR_HUMAN (1-375): 2.28e-53: 183: 19.74		HNRPD_HUMAN (20-314): 1.44e-52: 179: 33.33
+	Hs
		1048054 HNRPD_HUMAN (3-273): 3.96e-53: 182: 27.31		HNRPD_HUMAN (20-314): 1.44e-52: 179: 33.33
+	Hs
		516471 TIAR_HUMAN (1-375): 2.28e-53: 183: 19.74		PABP1_HUMAN (44-232): 1.13e-35: 138: 20.59
+	Hs
		516511 HNRPD_HUMAN (3-273): 3.96e-53: 182: 27.31		PABP1_HUMAN (44-232): 1.13e-35: 138: 20.59
+	Hs
		162127 ROAA_HUMAN (3-175): 4.34e-34: 131: 40.23		HNRDL_HUMAN (18-344): 8.21e-53: 181: 33.74
+	Hs
		161962 ROA2_HUMAN (82-182): 1.9e-25: 108: 35.64		HNRDL_HUMAN (18-344): 8.21e-53: 181: 33.74
+	Hs
		516663 ROAA_HUMAN (3-175): 4.34e-34: 131: 40.23		PABP1_HUMAN (44-232): 1.13e-35: 138: 20.59
+	Mm
		825781 HNRPD_MOUSE (3-273): 2.71e-53: 183: 27.31		ROA1_MOUSE (40-137): 1.39e-16: 81.3: 34.69
+	Hs
		1048086 HNRPD_HUMAN (3-273): 3.96e-53: 182: 27.31		RA1L2_HUMAN (40-137): 1.22e-16: 81.3: 33.67
+	Hs
		201699 MSI2H_HUMAN (2-304): 2.26e-52: 180: 31.35		MSI1H_HUMAN (44-335): 6.48e-16: 79.8: 15.36
+	Hs
		1288208 MSI2H_HUMAN (2-304): 2.26e-52: 180: 31.35		MSI2H_HUMAN (26-303): 1.72e-14: 75.2: 17.63
+	Hs
		516358 ROA2_HUMAN (82-182): 1.9e-25: 108: 35.64		PABP1_HUMAN (44-232): 1.13e-35: 138: 20.59
+	Hs
		1104173 ROAA_HUMAN (3-175): 4.34e-34: 131: 40.23		RA1L2_HUMAN (40-137): 1.22e-16: 81.3: 33.67