Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL
Interactor 2: MKNK2 (Q9HBH9)
MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)
Gene: MKNK2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 0.90 | 0.676 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16856496 |
| Identification Methods | two hybrid, affinity chromatography technology |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~VHL |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
